| Rnd | Team | Match Date | Home Team | Result | Away Team |
|---|
| 1 | Second XI | 2020-11-14 | Hampton | def | Murrumbeena |
| 3/127 | | 123 J Walker 36 |
| 2 | Second XI | 2020-11-21 | Murrumbeena | lost to | Bonbeach |
| 195 T Lamb 44 J Martin 25 | | 2/225 |
| 4 | Second XI | 2020-12-05 | Murrumbeena |  | McKinnon |
| 5/238 P Vadiveloo 54 W Kelly 103 Z Goold 35 | | 4/125 |
| 5 | Second XI | 2020-12-12 | Murrumbeena | | Mentone |
| 6/144 M Goold 25 J Williams 63 | | 9/143 J Walker 4/19 N Paranagama 2/13 J Harper 2/24 |
| 6 | Second XI | 2020-12-19 | Parkdale | | Murrumbeena |
| 9/171 J Walker 4/24 P Gupta 2/25 | | 4/172 T Dennis 56 Z Goold 28 J Walker 26* |
| 7 | Second XI | 2021-01-09 | Bentleigh | def | Murrumbeena |
| 5/182 | | 101 J Martin 27 |
| 9 | Second XI | 2021-01-23 | Bonbeach | | Murrumbeena |
| 87 N Paranagama 3/12 D Venturoni 2/19 T Fierenzi 3/10 J Harper 2/12 | | 6/132 C Anstee 43 T Dennis 25* |
| 10 | Second XI | 2021-01-30 | Murrumbeena | | Bentleigh |
| 6/194 J Williams 133* | | 193 Z Goold 4/30 J Harper 2/28 I Khan 2/45 |
| 11 | Second XI | 2021-02-07 | Murrumbeena | | Parkdale |
| 5/187 C Anstee 33 J Martin 75* D Venturoni 45 | | 186 N Paranagama 2/32 D Venturoni 4/25 J Harper 2/34 |
| 13 | Second XI | 2021-02-20 | Murrumbeena | lost to | Mordialloc |
| 186 Z Goold 56 J Walker 41 D Venturoni 28 | | 199 Z Goold 2/34 D Venturoni 3/54 N Paranagama 2/18 |
| 12 | First XI | 2021-02-21 | Murrumbeena | lost to | Beaumaris |
| 132 M Guruge 26 | | 7/149 T Kelly 2/20 N Karunarathne 3/32 |
| 14 | Second XI | 2021-02-27 | McKinnon | def | Murrumbeena |
| 185 Z Goold 2/28 D Venturoni 3/33 J Anstee 3/28 P Gupta 2/12 | | 140 C Anstee 36 |
